Anchored HTML File of EIDs

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway Name:Inositol phosphate metabolism ID:00562
C=57; O=2; E=0.07; R=29.10; rawP=0.0022; adjP=0.0060
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000241973	NA	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha	5297	ENSG00000241973
2	ENSG00000122126	NA	OCRL	oculocerebrorenal syndrome of Lowe	4952	ENSG00000122126

Database:KEGG pathway Name:Phosphatidylinositol signaling system ID:04070
C=78; O=2; E=0.09; R=21.27; rawP=0.0040; adjP=0.0060
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000241973	NA	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha	5297	ENSG00000241973
2	ENSG00000122126	NA	OCRL	oculocerebrorenal syndrome of Lowe	4952	ENSG00000122126

Database:KEGG pathway Name:Metabolic pathways ID:01100
C=1130; O=3; E=1.36; R=2.20; rawP=0.1554; adjP=0.1554
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000241973	NA	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha	5297	ENSG00000241973
2	ENSG00000122126	NA	OCRL	oculocerebrorenal syndrome of Lowe	4952	ENSG00000122126
3	ENSG00000140521	NA	POLG	polymerase (DNA directed), gamma	5428	ENSG00000140521

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).